How to Know if You Get a Blood Clot in Your Leg

DVT (Blood Clot in the Leg, Deep Vein Thrombosis) Definition and Facts

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Illustration of a blood clot forming in a blood vessel.

Blood clots ofttimes require medical treatment.

  • The definition of deep venous thrombosis (DVT) is a status in which a blood clot is embedded in 1 of the major deep veins of the lower legs, thighs, pelvis, or arm. A clot blocks blood circulation through these veins, which behave blood from the lower trunk back to the centre. The blockage can crusade acute pain, swelling, or warmth in the afflicted leg.
  • Blood clots in the veins can cause inflammation (irritation) called thrombophlebitis.
  • Severe complications of deep vein thrombosis occur when a clot breaks loose (or embolizes) and travels through the bloodstream, causing blockage of blood vessels (pulmonary arteries) in the lung. Called pulmonary embolism (PE), this tin lead to severe difficulty in breathing and even death, depending on the degree of blockage.
  • The U.South. Centers for Disease Control and Prevention (CDC) estimates as many equally 900,000 people could exist afflicted past DVT/PE each year in the U.s., and 60,000 to 100,000 Americans die of DVT/PE (likewise called venous thromboembolism).
  • Symptoms and signs of DVT occur in the leg with the blood clot, and include:
    • Swelling
    • Hurting
    • Redness
    • Warmth to the touch
    • Worsening leg hurting when bending the foot
    • Leg cramps (especially at night and/or in the calf)
    • Discoloration of skin
  • Causes of deep vein thrombosis include harm to the inside of a blood vessel due to trauma or other weather, changes in normal blood flow, or a rare state in which the blood is more likely than usual to clot (hypercoagulability).
  • Take a chance factors for DVT/PE include:
    • Prolonged sitting or immobility
    • Contempo surgery
    • Recent trauma to the lower body
    • Obesity
    • Middle attack or center failure
    • Pregnancy or contempo childbirth
    • High altitudes
    • Estrogen therapy or nascency control pills
    • Cancer
    • Rare genetic weather condition that affect claret clotting factors
    • Certain heart or respiratory weather
    • Advanced age
    • Medical weather that affect the veins
  • Doctors diagnose the condition using imaging tests such equally Doppler ultrasound, venography, impedance plethysmography, and CT scan.
  • Treatment of DVT in the leg is individualized for each patient. Usually, anticoagulation or claret-thinning medication is prescribed to prevent further jell formation and to minimize the risk that role of the blood clot will intermission off and travel to the lung and cause pulmonary embolism. New guidelines for various treatments were made by the ACCP (American Higher of Physicians) in 2016.
  • In rare cases, large deep venous thrombosis of the leg is treated with surgery in patients who cannot have blood thinners.
  • Prevention and prophylaxis of DVT involves managing risk factors.
    • Lose weight if overweight or obese
    • Avoid periods of prolonged immobility.
    • Keep the legs elevated while sitting down or in bed.
    • Avert high-dose estrogen pills.
    • Afterward surgery, get out of bed several times a day during the recovery period, use compression devices on the legs or elastic pinch socks/stockings.
    • Have heparin or warfarin (Coumadin, Jantoven) if prescribed to prevent clot formation.

What Are the Warning Signs and Symptoms of a DVT?

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DVT (Blood Clot in the Leg)

Symptoms of DVT (blood clot in the leg) include swelling, pain, redness, warmth to the impact, leg cramps, or bluish/whitish discoloration of the peel.

Signs and symptoms of a blood clot in the leg or deep vein thrombosis occur in the affected leg when a clot obstructs claret flow and causes inflammation. Signs and symptoms of DVT may include:

  1. Swelling
  2. Gradual onset of pain
  3. Redness
  4. Warmth to the impact
  5. Worsening leg pain when bending the pes
  6. Leg cramps, especially at night, and often starting in the calf
  7. Blue or whitish discoloration of peel

Some people with deep vein thrombosis practice not experience whatever symptoms.

What Causes DVTs?

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Causes of DVT

The three factors that may lead to claret clots are damage to the inside of a claret vessel, blockage of blood flow, and hypercoagulability (rare state).

Three factors may lead to the germination of a clot within a blood vessel:

  1. Impairment to the within of a blood vessel due to trauma or other conditions
  2. Changes in normal blood menstruation, including unusual turbulence, or partial or complete blockage of blood flow
  3. Hypercoagulability, a rare state in which the blood is more likely than usual to jell

Whatsoever event or condition that can atomic number 82 to blood vessel damage, hypercoagulability, or change in blood menstruum tin potentially cause deep vein thrombosis. The more common chance factors are:

  • Prolonged sitting, such equally during a long plane flight or machine ride
  • Prolonged bed rest or immobility, such as after injury or during illness (for example stroke)
  • Recent surgery, particularly orthopedic (specially hip, leg, or , human knee such as knee or hip replacement), gynecologic, heart, or abdominal surgery
  • Recent trauma to the lower body, such every bit fractures of the basic of the hip, thigh, or lower leg
  • Obesity
  • Heart attack or heart failure
  • Pregnancy or recent childbirth
  • Being at very high altitude, greater than fourteen,000 feet
  • Use of estrogen therapy or birth control pills
  • Cancer
  • Rare inherited genetic conditions that lead to changes in certain blood clotting factors
  • Sure heart or respiratory conditions
  • Advanced historic period
  • Medical conditions that touch the veins such as vasculitis (inflammation of the vein walls), varicose veins
  • Superficial venous thrombosis (SVT) occurs when a claret clot forms in a superficial vein near the surface of the trunk. While not the same as DVT (which occurs in deep veins) it tin exist a risk factor for DVT/PE
  • Disseminated intravascular coagulation (DIC), a medical condition in which blood clotting occurs inappropriately, commonly is acquired by overwhelming infection or organ failure

If an individual has one deep vein thrombosis, they are 33% more than probable to develop a 2d deep vein thrombosis within 10 years.

QUESTION

Deep vein thrombosis (DVT) occurs in the _______________. Meet Respond

When Is a DVT a Medical Emergency?

Call the doctor immediately if a blood clot is suspected.

  • Although a deep vein thrombosis may resolve on its own, the life-threatening consequences of a clot reaching the lung, chosen pulmonary embolism, are astringent enough to warrant seeking medical attending immediately.
  • The doctor may tell the patient to become immediately to a hospital emergency department.

If a person has leg pain or swelling with any run a risk factors, go to a hospital emergency department immediately.

Call 9-one-1 if you or someone you know with a current deep vein thrombosis, previous deep vein thrombosis, or other DVT/PE chance cistron begins having chest pain, shortness of jiff, difficulty animate, fainting, or any other concerning symptom.

Which Types of Doctors Treat DVTs?

The initial diagnosis of DVT is unremarkably fabricated by the general practitioner, internist, family practitioner, or an emergency medicine specialist.

Depending on the severity of the DVT/PE, or the need for intervascular or surgical intervention, one may exist referred to a vascular surgeon or an interventional radiologist. Other specialists involved in the care may involve a pulmonologist (a physician who specializes in the lungs), or a hematologist (specialist in blood disorders).

What Tests Diagnose DVTs?

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Upon hearing the patient'southward symptoms, the physician may suspect the patient has a deep vein thrombosis, especially if any risk factors are present.

No authentic blood test is available to diagnose deep vein thrombosis. A diversity of imaging tests are used to confirm the diagnosis.

  • Doppler ultrasound: Using high-frequency sound waves, this system can visualize the big, proximal veins and discover a jell if 1 is present. Painless and without complications, this is the nigh usually used method to diagnose deep vein thrombosis. However, sometimes the test tin can miss a clot, especially in the smaller veins.
  • Venography: A liquid dye is injected into the veins for imaging studies. It highlights blockage of blood menses past a jell. This is the most accurate test, but as well the most uncomfortable and invasive. It is rarely done today because of the availability of improved ultrasound technology.
  • Impedance plethysmography: Electrodes are used to measure out volume changes inside veins. Considering this examination does not find clots better than ultrasound and is harder to perform, it is rarely used.
  • CT scan: This is a blazon of X-ray that gives a very detailed look at the leg veins in cantankerous section and tin observe clots. It is rarely used for this purpose as it is more than hard to interpret and is time consuming. The CT scan is more useful for identification of claret clots in the lung.

What Is the Treatment for DVTs?

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The treatment of blood clots depends upon their location in the torso. Most usually, anticoagulation or blood-thinning medication is prescribed to prevent further jell formation and to minimize the adventure that part of the blood clot will break off and travel to the lung and cause pulmonary embolism, or pulmonary embolism. Treatment of deep venous thrombosis in the leg is often individualized for each patient depending upon the clinical situation and other medical conditions that may be present. The following is how diverse drugs and therapies have been used. New guidelines take been written in 2016 to aid optimize treatments in patients with or without cancer, lower extremity DVT and pulmonary embolism, and for other individual patient circumstances.

Treatment of deep venous thrombosis in the leg is oftentimes individualized for each patient depending upon the clinical state of affairs and other medical conditions that may be present.

Anticoagulation is usual the handling of choice and is a two stage process. Depression molecular weight heparin (enoxaparin [Lovenox], dalteparin [Fragmin]) injections are started to begin immediate claret thinning. At the same time, warfarin (Coumadin, Jantoven) is prescribed (an oral anticoagulation medication that takes a few days to become effective and adequately anticoagulate the blood). Blood tests (prothrombin time or international normalized ratio [INR]) are used to measure the effectiveness of the warfarin therapy. When the INR reaches the appropriate level, the heparin injections are discontinued.

Rivaroxaban (Xarelto) is a medication chosen a selective Cistron Xa inhibitor that is an oral tablet indicated for the treatment of DVT. It may be used as a treatment and a preventative prophylaxis for blood clots instead of warfarin.

Apixaban (Eliquis) and dabigatran (Pradaxa) also are drugs used to prevent blood clots and treat astute DVT.

If possible, the treatment of uncomplicated deep venous thrombosis in an individual is accomplished as an outpatient. Instruction is provided to the patient and family to teach them how to administer the injection, and the patient is instructed to return to their family physician or the hospital for appropriate monitoring (claret tests). Some patients will need to be admitted to the hospital if they have meaning underlying medical illnesses, are meaning, or are unable to administer the heparin injections.

The duration of anticoagulation therapy depends upon the circumstances that led to the development of the blood clot. If there were temporary adventure factors, for example a long trip or recent immobility because of injury or illness, handling may final 3 to 6 months. However, if the crusade is unknown or if there is the chance for recurrent jell germination, medication may be required for more than 12 months.

Non all DVTs require anticoagulation. Considering small clots located in veins beneath the knee have a low risk of embolizing to the lung, it tin be possible to observe the patient without giving medications. Using serial ultrasound tests of the veins, the clot tin be monitored to see whether it is extending and growing or whether it is stable and needs no farther treatment.

Blood clots located in the femoral vein near the groin that extend into the iliac vein in the abdomen may require more aggressive treatment with thrombolytic (thrombo=clot + lysis=breakdown) therapy. Clot-busting drugs (alteplase [Activase], streptokinase [Streptase]) may exist injected direct into the clot itself. This ordinarily requires a specialist (a vascular surgeon or an interventional radiologist) who tin can use fluoroscopy or real fourth dimension X-rays to position a catheter or tube into the affected vein where the clot resides and drip the medication in over a period of time to deliquesce the jell and prevent it from traveling to the lung.

Similar situations can be in the arm. DVTs in a higher place the elbow are usually treated with blood-thinner medications equally described to a higher place, while clots in the subclavian vein, located just below the collarbone, may be considered for thrombolytic therapy.

Considering of underlying medical conditions, some people may not be able to take anticoagulation medications and may require an alternative treatment instead of medication. Those who have gastrointestinal bleeding (bleeding from the breadbasket or bowel), intracranial bleeding (bleeding inside the brain or surrounding tissues), or who have had contempo major trauma potentially could bleed to expiry if anticoagulation medications are prescribed. The culling for leg DVT handling in these situations may exist an junior vena cava filter. The vena cava is the large vein that collects blood from the lower body just earlier information technology enters the heart. A filter can be placed into the vena cava to trap any clots that might break off and prevent them from traveling to the middle and and then to the lungs.

Compression stockings or socks are useful in preventing a complication of a leg blood clot chosen post-thrombotic syndrome or postphlebitis syndrome, in which the affected leg swells and becomes chronically painful. These stockings may be purchased over-the-counter or can be custom fitted. It is recommended they be worn for at least a year after the diagnosis of deep venous thrombosis.

What Medications Care for DVTs?

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Warfarin (Coumadin) is an oral medication taken to thin or anticoagulate the blood. It may take a few days for its activeness to take upshot. The dose needs to be individualized for each person, and blood clotting must be monitored routinely since changes in diet, activeness, and the administration of other medications may impact the levels of warfarin. Blood tests (usually international normalized ratio [INR]) are done routinely to monitor the blood-thinning effects and help the health care professional person select the appropriate warfarin dose. Ideally, the INR should be kept in a range between 2.0 and iii.0. Blood tests are done weekly until the INR stabilizes and then are done every two weeks to every month.

Enoxaparin (Lovenox) is a low molecular weight heparin injected beneath the skin to thin the blood. The dose is usually 1 milligram per kilogram of weight injected twice daily or 1.5 milligrams per kilogram injected once daily. Enoxaparin usually is considered a temporary medication to exist used to thin the blood while warfarin begins to take effect; notwithstanding, it may be used over the long term in some patients with cancer. Fondaparinux (Arixtra) is another injectable chemically related to low molecular weight heparin, used for DVT prevention and treatment.

If a woman develops a DVT/PE while pregnant it is unremarkably treated with heparin simply, because warfarin is dangerous to administrate during pregnancy.

Rivaroxaban (Xarelto) is a newer medication, which belongs to the selective Gene Xa inhibitor class of drugs, is an oral tablet for the treatment of DVT. It may be used as a treatment and a preventive therapy for blood clots.

Apixaban (Eliquis), dabigatran (Pradaxa), and Edoxaban (Savaysa, Lixiana) are also used to foreclose claret clots and treat acute DVT.

When Is Surgery Necessary for a DVT?

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Surgery is a rare option in treating large deep venous thrombosis of the leg in patients who cannot take blood thinners or who have developed recurrent blood clots while on anticoagulant medications. The surgery is usually accompanied by placing an IVC (inferior vena cava) filter to forestall future clots from embolizing to the lung.

Phlegmasia cerulea dolens describes a situation in which a claret clot forms in the iliac vein of the pelvis and the femoral vein of the leg, obstructing almost all blood return and compromising blood supply to the leg. In this example surgery may be considered to remove the clot, but the patient will also require anticoagulant medications.

SLIDESHOW

Spider & Varicose Veins: Causes, Before and Later on Treatment Images See Slideshow

Do I Need to Follow-upward with My Physician Afterward DVT Treatment?

A person who has had a deep vein thrombosis may be asked to return for follow-upward. Doppler ultrasounds or other imaging studies may be performed if the leg swelling persists or if the symptoms recur. During anticoagulant handling, it is often advised to accept the following measures:

  • Accept the prescribed amount of medication as directed by a physician. Exercise non miss or add doses.
  • Follow the doctor'southward instructions closely virtually when to become lab tests for claret coagulation.
  • Inquire the physician before starting or stopping any medication or supplement, including over-the-counter (OTC) medications. Many medicines and supplements increase or otherwise interfere with the effect of anticoagulants.
  • Enquire what foods should be avoided, because some foods may change the effectiveness of blood-thinning drugs.
  • Wearing a MedicAlert bracelet with information most any anticoagulants ane is taking is brash.
  • People on anticoagulant therapy should inform any other medical professionals including dentists or podiatrists before undergoing any process.

What Is the Chance of Having Another DVT?

Most DVTs resolve on their own. If a pulmonary embolism (PE) occurs, the prognosis can be more than astringent.

  • About 25% of people who have a PE will die suddenly, and that will be the only symptom.
  • Most 23% of people with PE will die within three months of diagnosis, just over 30% will die later six months, and there is a 37% mortality (decease) rate at 1 yr after beingness diagnosed.

If an individual has had i deep vein thrombosis, they are more likely than the average person to have some other deep vein thrombosis.

  • The CDC estimates 33% of people with DVT/PE will accept a recurrence within 10 years.
  • Recurrence of DVT is more common in patients with risk factors such as cancer or inherited blood-clotting problems. Recurrence is less common in patients who have curt-term risk factors, such as surgery or temporary inactivity.
  • Closely follow the prevention instructions from the doctor.
  • Anticoagulant therapy lowers the decease rate from pulmonary embolism significantly.

How Can a DVT Be Prevented?

The key to prevention of DVT is to reverse any adventure factors, for example:

  • Lose weight if overweight or obese.
  • Avoid periods of prolonged immobility. Become up and motility around every 15 to thirty minutes during long plane flights. Practice simple stretching exercises while seated. Brand frequent stops and get out of the car when driving long distances.
  • Keep the legs elevated while sitting down or in bed.
  • Avert high-dose estrogen pills, unless they are deemed necessary by the doctor.

In the case of recent surgery, preventive treatment may exist prescribed to avoid formation of a clot.

  • The patient may be instructed to get out of bed several times a solar day during the recovery catamenia.
  • Sequential compression devices (SCDs) may be placed on the legs. Their squeezing action has been shown to reduce the probability of clot germination. The patient may also be given elastic compression socks or stockings to vesture.
  • Low-molecular-weight heparin or depression-dose warfarin may be prescribed to prevent jell formation.

DVT picture

What Are the Symptoms and Signs of a Pulmonary Embolism (Blood Clot in the Lung)?

Warning signs and symptoms of a blood clot in the lung or pulmonary embolism include:

  1. A very sharp stabbing hurting in the chest
  2. Shortness of breath.
  3. Cough.
  4. Sweating.
  5. Passing out.

A blood jell in the lung is a medical emergency and needs to be treated correct away.

Reviewed on 6/4/2020

References

LiP, GYH MD. Approach to the diagnosis and therapy of lower extremity deep vein thrombosis. UpToDate. Updated: Sep 29, 2019.
<https://world wide web.uptodate.com/contents/approach-to-the-diagnosis-and-therapy-of-lower-extremity-deep-vein-thrombosis>

Centers for Disease Control and Prevention. Venous Thromboembolism. (Blood Clots).

FDA Prescribing Information. SAVAYSA™ (edoxaban).
<http://www.accessdata.fda.gov/drugsatfda_docs/label/2015/206316lbl.pdf>

FDA Prescribing Information. ARIXTRA® (fondaparinux sodium) infection.
<http://world wide web.accessdata.fda.gov/drugsatfda_docs/label/2005/021345s010lbl.pdf>

Dentali, F., et al. "Pulmonary embolism severity alphabetize accurately predicts long-term bloodshed rate in patients hospitalized for astute pulmonary embolism."

Journal of Thrombosis and Haemostasis

. xi.12 (2013): 2103-2120.

Litzendorf, Chiliad. East. and B Satiani. "Superficial venous thrombosis: disease progression and evolving treatment approaches." Vascular Wellness and Gamble Management. 7 (2011): 569-575.

Lucena, J., et al. "Pulmonary embolism and sudden-unexpected death: prospective study on 2477 forensic autopsies performed at the Found of Legal Medicine in Seville." Journal of Forensic and Legal Medicine. xvi.4 (2009): 196-201.

MedlinePlus. Deep Vein Thrombosis. Thompson, B.T., Doc. "Overview of astute pulmonary embolism in adults." Updated: Aug 08, 2016.
<http://www.uptodate.com/contents/overview-of-acute-pulmonary-embolism-in-adults>

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